5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-13C2,15N

• Catalog No.: A611702
• M. F.: C9H14N4O5
• M. W.: 261.20997857
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 5-amino-1-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl](4,5-^1^3C₂,3-^1^5N)-1H-imidazole-4-carboxamide
• IUPAC Traditional name: 5-amino-1-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl](4,5-^1^3C₂,3-^1^5N)imidazole-4-carboxamide
• Synonyms: GP 1-110-13C2,15N; 5-Amino-4-imidazolecarboxamide Riboside-13C2,15N; Arasine-13C2,15N; AICAR-13C2,15N; 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-13C2,15N; Acadesine-13C2,15N; NSC 105823-13C2,15N

PROPERTIES

• Apperance: White Solid
• Melting Point: 187-192°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardi

REFERENCES

• Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993)
• Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)