17-Amino Geldanamycin

• Catalog No.: A609700
• CAS Number: 64202-81-9
• M. F.: C28H39N3O8
• M. W.: 545.62456
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (4E,6Z,8R,9S,10E,12S,13R,14R,16R)-19-amino-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• IUPAC Traditional name: (4E,6Z,8R,9S,10E,12S,13R,14R,16R)-19-amino-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
• Synonyms: NSC 255109; 17-Amino-17-demethoxygeldanamycin; 17-Aminogeldanamycin; 17AG

DATABASE IDS

• CAS Number: 64202-81-9

PROPERTIES

• Apperance: Dark Purple Solid
• Melting Point: 178-180°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

The active metabolite of 17-(Allylamino)geldanamycin (17AAG).

REFERENCES

• Kamal, A., et al.: Nature, 425, 407 (2003)
• Goetz, M., et al.: J. Clin. Oncol., 23, 1078 (2003)
• Bagatell, R., et al.: Clin. Cancer Res., 13, 1783 (2003)
• Burger, A., et al.: Cancer Lett., 245, 11 (2003)