N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-Deoxyguanosine

• Catalog No.: A606815
• CAS Number: 142038-30-0
• M. F.: C21H22N10O4
• M. W.: 478.46398

SYNONYMS

• IUPAC name: 2-({2-amino-3,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-5-yl}amino)-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
• IUPAC Traditional name: 2-({2-amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl}amino)-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
• Synonyms: N2-MeIQx-Deoxyguanosine; N-(2-Amino-3,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-5-yl)-2'-deoxyguanosine

DATABASE IDS

• CAS Number: 142038-30-0

DETAILS

Description (English)

Heterocyclic amines, such as 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), are mutagenic/carcinogenic compounds formed during the cooking of protein-rich foods. An adduct of the potent dietary mutagen MeIQx.

REFERENCES

• Farmer, P., et al.: Arch. Toxicol., 60, 251 (1987)
• Chou, H., et al.: Cancer Res., 55, 525 (1987)
• Frantz, C., et al.: Carcinogenesis, 16, 367 (1987)