7-Amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio]methyl]cephalosporanic Acid

• Catalog No.: A604870
• CAS Number: 58909-56-1
• M. F.: C12H13N5O5S2
• M. W.: 371.39212

SYNONYMS

• IUPAC name: (6R,7R)-7-amino-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• IUPAC Traditional name: (6R,7R)-7-amino-3-{[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Synonyms: (6R-trans)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7R)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

DATABASE IDS

• CAS Number: 58909-56-1

DETAILS

Description (English)

An intermediate in the synthesis of cephalosporin antibiotics, Ceftriaxone (C245000) and Cefixime (C242800).

REFERENCES

• Hecker, S., et al.: J. Antibiot., 53, 1272 (2000)
• Tsushima, M., et al.: Bioorg. Med. Chem., 8, 2781 (2000)
• Ishikawa, T., et al.: Bioorg. Med. Chem., 11, 2427 (2000)
• Appelbaum, P., et al.: Clin. Microbiol. Infect., 12, 3 (2000)