2-Amino-5,6-dichloro-3(4H)-quinazoline Acetic Acid Hydrobromide (Anagrelide Impurity B)

• Catalog No.: A604745
• CAS Number: 1194434-39-3
• M. F.: C10H10BrCl2N3O2
• M. W.: 355.0153
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-(2-amino-5,6-dichloro-3,4-dihydroquinazolin-3-yl)acetic acid hydrobromide
• IUPAC Traditional name: (2-amino-5,6-dichloro-4H-quinazolin-3-yl)acetic acid hydrobromide
• Synonyms: Anagrelide Impurity B

DATABASE IDS

• CAS Number: 1194434-39-3

PROPERTIES

• Apperance: White Solid
• Melting Point: >300°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Anagrelide impurity B. Quinazolines derivatives are attractive targets because they form an important component of pharmacologically active compounds and are associated with a wide spectrum of biological activities ranging from anticonvulsant and antibact

REFERENCES

• Molamas, M.S., et al.: J. Med. Chem., 34, 1492 (1991)
• Brogden, R.N., et al.: Drugs, 47, 809 (1991)
• Brase, S., et al.: Bioorg. Med. Chem. Lett., 10, 2415 (1991)