(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

• Catalog No.: A604380
• CAS Number: 847926-88-9
• M. F.: C14H12N2O
• M. W.: 224.25788

SYNONYMS

• IUPAC name: (10S)-10-amino-8-azatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,12,14-hexaen-9-one
• IUPAC Traditional name: (10S)-10-amino-8-azatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,12,14-hexaen-9-one
• Synonyms: (7S)-7-Amino-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

DATABASE IDS

• CAS Number: 847926-88-9

DETAILS

Description (English)

A building block for γ-secretase inhibitors for treatment of Alzheimer's disease. Several γ-secretase inhibitors have been described that contain this compound.

REFERENCES

• Beher, D., et al.: Exp. Opin. Investig. Drugs, 14, 1385 (2005)
• Fauq, A., et al.: Bioorg. Med. Chem. Lett., 17, 6392 (2005)