(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate

• Catalog No.: A603150
• CAS Number: 209977-56-0
• M. F.: C9H12N2O6
• M. W.: 244.20138
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2-amino-3-[3-(carboxymethoxy)-5-methyl-1,2-oxazol-4-yl]propanoic acid
• IUPAC Traditional name: 2-amino-3-[3-(carboxymethoxy)-5-methyl-1,2-oxazol-4-yl]propanoic acid
• Synonyms: α-Amino-3-(carboxymethoxy)-5-methyl-4-isoxazolepropanoic Acid Hydrate (2:3); AMOA

DATABASE IDS

• CAS Number: 209977-56-0

PROPERTIES

• Apperance: White Crystalline Solid
• Melting Point: 230°C dec.
• Solubility: Hot Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as represented by binding of [3H]-CPP, [3H]-gly or [3H]-MK-801. AMOA also

REFERENCES

• Frandsden, A., et al.: J. Neurochem., 55, 1821 (1990)
• Krogsgaard-Larsen, P., et al.: J. Med. Chem., 34, 123 (1990)
• Berg, M., et al.: Acta Neuropathalogica, 81, 255 (1991)