5-Amino-1-tert-butyl-3-(1'-naphthylmethyl)-4-cyanopyrazole

• Catalog No.: A603002
• CAS Number: 221243-77-2
• M. F.: C19H20N4
• M. W.: 304.3889
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 5-amino-1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazole-4-carbonitrile
• IUPAC Traditional name: 5-amino-1-tert-butyl-3-(naphthalen-1-ylmethyl)pyrazole-4-carbonitrile
• Synonyms: 5-Amino-1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazole-4-carbonitrile5-Amino-1-(tert-butyl)-3-(1-naphthalenylmethyl)-1H-pyrazole-4-carbonitrile

DATABASE IDS

• CAS Number: 221243-77-2

PROPERTIES

• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A highly potent (IC50=1.5nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.

REFERENCES

• Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999)