Ambroxol Cyclic Impurity Hydrochloride

• Catalog No.: A575910
• M. F.: C14H18Br2N2O
• M. W.: 390.11352

SYNONYMS

• IUPAC name: (1r,4r)-4-(6,8-dibromo-1,2,3,4-tetrahydroquinazolin-3-yl)cyclohexan-1-ol
• IUPAC Traditional name: (1r,4r)-4-(6,8-dibromo-2,4-dihydro-1H-quinazolin-3-yl)cyclohexan-1-ol
• Synonyms: NA 873 Hydrochloride; Ambroxol EP Impurity B Hydrochloride; trans-4-(6,8-Dibromo-1,4-dihydro-3(2H)-quinazolinyl)cyclohexanol Hydrochloride

DETAILS

Description (English)

Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).

REFERENCES

• Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978)
• Nieder, M. et al.: HRC & CC, 9, 561 (1978)
• Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (1978)