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AM-2233-d5
Catalog No.	A575852	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C22H23IN2O	Telephone	+1 (416) 665-9696
M. W.	458.33529	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	Controlled Substance, -20°C Freezer, Under Inert Atmosphere	Chembase ID: 159761

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SYNONYMS

IUPAC name

3-(2-iodobenzoyl)-1-{[1-(²H₃)methylpiperidin-2-yl](²H₂)methyl}-1H-indole

IUPAC Traditional name

3-(2-iodobenzoyl)-1-{[1-(²H₃)methylpiperidin-2-yl](²H₂)methyl}indole

Synonyms

(2-Iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone-d5

1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodobenzoyl)-1H-indole-d5

DATABASE IDS

PROPERTIES

Certificate of Analysis	Download
Apperance	Off-White Solid
Melting Point	146-148°C
Solubility	Chloroform
Solubility	Methanol
MSDS Link	Download
Storage Condition	Controlled Substance, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled AM-2233 (A575850). A potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. (AM2233) had a very high affinity for the rat CB1 receptor, with most of the affinity residing with the (R)-enan

REFERENCES

Neumeyer, J., et al.: J. Med. Chem., 33, 521 (1990)
D'Ambra, T., et al.: Bioorg. Med. Chem. Lett., 6, 17 (1990)
Schatz, A., et al.: Toxicol. Appl. Pharmacol., 142, 278 (1990)