Alosetron-d3 Hydrochloride

• Catalog No.: A575502
• CAS Number: 1189919-71-8
• M. F.: C17H19ClN4O
• M. W.: 330.81196

SYNONYMS

• IUPAC name: 5-(^2H₃)methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one hydrochloride
• IUPAC Traditional name: 5-(^2H₃)methyl-2-[(5-methyl-3H-imidazol-4-yl)methyl]-3H,4H-pyrido[4,3-b]indol-1-one hydrochloride
• Synonyms: GR 68755X-d3; GR 68755-d3; 2,3,4,5-Tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride; Lotronex-d3

DATABASE IDS

• CAS Number: 1189919-71-8

DETAILS

Description (English)

Labelled serotonin 5HT3-receptor antagonist. Used in treatment of irritable bowel syndrome.

REFERENCES

• Camilleri, M., et al.: Lancet, 355, 1035 (2000)
• Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2000)
• Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2000)
• Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2000)
• Gleeson, M., et al.: J. Med. Chem., 50, 101 (