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7-Allyl-7,8-dihydro-8-oxoguanosine(Loxoribine)_Molecular_structure_CAS_121288-39-9)
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7-Allyl-7,8-dihydro-8-oxoguanosine(Loxoribine)

Catalog No. A550000 Name Toronto Research Chemicals
CAS Number 121288-39-9 Website http://www.trc-canada.com
M. F. C13H17N5O6 Telephone +1 (416) 665-9696
M. W. 339.30398 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator, Under Inert Atmosphere Chembase ID: 159684

SYNONYMS

IUPAC name
2-amino-9-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-(prop-2-en-1-yl)-6,7,8,9-tetrahydro-1H-purine-6,8-dione
IUPAC Traditional name
2-amino-9-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-(prop-2-en-1-yl)-1H-purine-6,8-dione
Synonyms
7-Allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1H-purine-6,8-dione, Loxoribine

DATABASE IDS

CAS Number 121288-39-9

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 227-230°C
Solubility DMSO
MSDS Link Download
Storage Condition Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)
7-Allyl-7,8-dihydro-8-oxoguanosine (Loxoribine) is a small-molecule immunostimulant. Loxoribine is a toll-like receptor 7 (TLR7) agonist; induces immune cell activation and increases cytokine production. Loxoribine displays antitumor and antiviral activi

REFERENCES

  • Goodman, M.G., et al.: J. Immunol., 135, 3284 (1985)
  • Reitz, A. B., et al.: J. Med. Chem., 37, 3561 (1994)