(3α)-Allopregnanolone-d5

• Catalog No.: A547102
• M. F.: C21H34O2
• M. W.: 318.49346

SYNONYMS

• IUPAC name: 1-[(1S,2S,5R,7S,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]ethan-1-one
• IUPAC Traditional name: 1-[(1S,2S,5R,7S,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]ethanone
• Synonyms: (+)-3α-Hydroxy-5α-pregnan-20-one-d5; Allopregnanolone-d5; 3α,5α-Tetrahydroprogesterone-d5; 3α,5α-THP-d5; (3α,5α)-3-Hydroxypregnan-20-one-d5; 3α-Hydroxy-5α-dihydroprogesterone-d5; 3α-Hydroxy-5α-pregnan-20-one-d5; 3α-Hydroxy-5α-pregnane-20-one-d5; 5α-Pregnan-3α-ol-20-one-d5; 5α-Pregnane-3α-ol-20-one-d5; Allopregnan-3α-ol-20-one-d5; Allotetrahydroprogesterone-d5

DETAILS

Description (English)

Labelled (3α)-Allopregnanolone. (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the

REFERENCES

• Puja, G. et al.: Neuron, 4, 759 (1990)
• Belelli, D. et ael. Neurosteroid, 6, 565 (1990)
• Viapiano, M. et al.: Neurochem. Res., 23, 155 (1990)