Aldosterone-d7 (Major)

• Catalog No.: A514702
• M. F.: C21H28O5
• M. W.: 360.44402
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: (1S,2R,10S,11S,14S,15S,17S)-17-hydroxy-14-[2-hydroxy(^2H₂)acetyl]-2-methyl-5-oxo(4,4,6,8,8-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-ene-15-carbaldehyde
• IUPAC Traditional name: (1S,2R,10S,11S,14S,15S,17S)-17-hydroxy-14-[2-hydroxy(^2H₂)acetyl]-2-methyl-5-oxo(4,4,6,8,8-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-ene-15-carbaldehyde
• Synonyms: 18-Oxocorticosterone-d7; Elektrocortin-d7; 18-Formyl-11β,21-dihydroxy-4-pregnene-3,20-dione-d7; Electrocortin-d7; (11β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al-d7; 11β,21-Dihydroxypregn-4-ene-3,18,20-trione-d7; Aldocortene-d7; NSC 73856-d7; Reichstein X-d7

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 172-175°C
• Solubility: Chloroform
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

A labelled adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorp

REFERENCES

• Simpson, et al.: Experienta, 9, 333 (1953)
• Morel, A., et al.: Nature, 356, 523 (1953)
• Arima, S., et al.: Clin. Exp. Nephrol., 7, 172 (1953)
• Hirasawa, A., et al.: Eur. J. Pharmacol., 267, 71 (1953)
• Hiroyama, M., et al.: Mol. Endocrinol., 21, 247 (2007)