Home > Compound List > Product Information
Agomelatine_Molecular_structure_CAS_138112-76-2)
Click picture or here to close

Agomelatine

Catalog No. A430000 Name Toronto Research Chemicals
CAS Number 138112-76-2 Website http://www.trc-canada.com
M. F. C15H17NO2 Telephone +1 (416) 665-9696
M. W. 243.30098 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 72589

SYNONYMS

IUPAC name
N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
IUPAC Traditional name
agomelatine
Synonyms
N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide
N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide
Valdoxan
S 20098

DATABASE IDS

CAS Number 138112-76-2

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 107-109°C
Solubility Chloroform
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human

REFERENCES

  • Yous, S., et al.: J. Med. Chem., 35, 1484 (1992)
  • Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (1992)
  • Cajochen, C., et al.: J. Pineal Res., 35, 149 (1992)