S-(5'-Adenosyl)-L-methionine-13C5 Chloride

• Catalog No.: A291533
• M. F.: C15H23ClN6O5S
• M. W.: 439.86159419

SYNONYMS

• IUPAC name: [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy(2,3,4,5-^1^3C₄)oxolan-2-yl](^1^3C)methyl})methylsulfanium chloride
• IUPAC Traditional name: [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy(2,3,4,5-^1^3C₄)oxolan-2-yl](^1^3C)methyl})methylsulfanium chloride
• Synonyms: S-Adenosylmethionine-13C5 Chloride; 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine-13C5 Chloride; Active Methionine-13C5 Chloride; S-Adenosyl-L-methionine-13C5 Chloride; 5'-[(L-3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine-13C5 Chloride; Ademetionine-13C5 Chloride; L-S-Adenosylmethionin-13C5 Chloride

DETAILS

Description (English)

Labelled S-(5'-Adenosyl)-L-methionine Chloride (A291530). Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver

REFERENCES

• Friedel, H., et al.: Drugs, 38, 389 (1989)
• Lu, S., et al.: Int. J. Biochem. Cell Biol., 32, 391 (1989)
• Amin, K., et al.: Pharm. Res., 18, 914 (1989)