S-(5'-Adenosyl)-L-methionine-d3 Disulfate Salt (Synthetic)(Mixture of Diastereomers)

• Catalog No.: A291532
• M. F.: C15H24N6O9S2
• M. W.: 496.51586

SYNONYMS

• IUPAC name: [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})(^2H₃)methylsulfanium hydrogen sulfate
• IUPAC Traditional name: [(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})(^2H₃)methylsulfanium hydrogensulfate
• Synonyms: S-Adenosyl-L-methionine-d3 Disulfate; 5'-[[(3S)-3-Amino-3-carboxypropyl](methyl-d3)sulfonio]-5'-deoxyadenosine Disulfate; Active Methionine-d3 Disulfate; Ademetionine-d3 Disulfate; L-S-Adenosylmethionin-d3 Disulfate; 5'-[(L-3-Amino-3-carboxypropyl)(methyl-d3)sulfonio]-5'-deoxyadenosine Disulfate; S-Adenosylmethionine-d3 Disulfate

DETAILS

Description (English)

Labelled S-(5'-Adenosyl)-L-methionine. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all m

REFERENCES

• Friedel, H., et al.: Drugs, 38, 389 (1989)
• Lu, S., et al.: Int. J. Biochem. Cell Biol., 32, 391 (1989)
• Amin, K., et al.: Pharm. Res., 18, 914 (1989)