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Adefovir Dipivoxil

Catalog No. A280465 Name Toronto Research Chemicals
CAS Number 142340-99-6 Website http://www.trc-canada.com
M. F. C20H32N5O8P Telephone +1 (416) 665-9696
M. W. 501.470541 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 599

SYNONYMS

IUPAC name
[({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl 2,2-dimethylpropanoate
IUPAC Traditional name
adefovir dipivoxil
Synonyms
2,2-Dimethyl-propanoic Acid 1,1'-[[[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphinylidene]bis(oxymethylene)] Ester
bis(POM)-PMEA
Preveon
Hepsera

DATABASE IDS

CAS Number 142340-99-6

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 101-103°C
Solubility DMSO
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI).

REFERENCES

  • Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009)
  • Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2009)
  • Ming, X., et al.: Biochem. Pharmacol., 79, 455 (2009)