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N-(5-Adamant-1-yl-methoxy)pentyl Deoxynojirimycin_Molecular_structure_CAS_216758-20-2)
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N-(5-Adamant-1-yl-methoxy)pentyl Deoxynojirimycin

Catalog No. A210000 Name Toronto Research Chemicals
CAS Number 216758-20-2 Website http://www.trc-canada.com
M. F. C22H39NO5 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
(3R,4R)-1-[5-(adamantan-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
IUPAC Traditional name
(3R,4R)-1-[5-(adamantan-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
Synonyms
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-(tricyclo[3.3.1.13,7]dec-1-ylmethoxy)pentyl]-3,4,5-piperidinetriol

DATABASE IDS

CAS Number 216758-20-2

PROPERTIES

Certificate of Analysis Download
Apperance Off White Foam
Solubility Ethanol
Solubility Methanol
MSDS Link Download

DETAILS

Description (English)
A powerful inhibitor of the non-lysomal glucoceramidase at nanomolar concentrations. At these low concentrations, the lysosomal glucocerebrosidase and a-glucosidase, the glucoceramide synthetase, and the N-linked glycantrimming a-glucosidases of the endop

REFERENCES

  • Jeckel, D., et al.: J. Cell Biol., 117, 259 (1992)
  • Kato, A., et al.: J. Med. Chem., 48, 2036 (1992)
  • Sakabe, K., et al.: J. Biol. Chem., 285, 34460 (1992)