1-Acetyl-2,2,5,5-tetramethyl-Δ3-(pyrroline-15N)-3-methyl Methanethiosulfonate

• Catalog No.: A188602
• M. F.: C12H21NO3S2
• M. W.: 292.4234489

SYNONYMS

• IUPAC name: 1-{3-[(methanesulfonylsulfanyl)methyl]-2,2,5,5-tetramethyl-2,5-dihydro(1-^1^5N)-1H-pyrrol-1-yl}ethan-1-one
• IUPAC Traditional name: 1-{3-[(methanesulfonylsulfanyl)methyl]-2,2,5,5-tetramethyl(1-^1^5N)pyrrol-1-yl}ethanone
• Synonyms: Methanesulfonothioic Acid S-[(1-Acetyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-(pyrrol-15N)-3-yl)methyl] Ester

DETAILS

Description (English)

A highly reactive thiol-specific spin-label analogue. A specific conformational probe of thiol site structure by virtue of its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study.

REFERENCES

• Berengian, A., et al.: J. Biol. Chem., 274, 6305 (1999)
• Gross, A., et al.: Biochemistry, 38, 10324 (1999)
• Dobson, C., et al.: Nature, 426, 884 (1999)
• Dong, J., et al: Science, 308, 1023 (1999)