O-Acetyl Scopolamine Hydrobromide

• Catalog No.: A187825
• CAS Number: 5027-67-8
• M. F.: C19H24BrNO5
• M. W.: 426.30156

SYNONYMS

• IUPAC name: (1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,^4]nonan-7-yl (2S)-3-(acetyloxy)-2-phenylpropanoate hydrobromide
• IUPAC Traditional name: (1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,^4]nonan-7-yl (2S)-3-(acetyloxy)-2-phenylpropanoate hydrobromide
• Synonyms: Scopolamine Acetate Hydrobromide; NSC 172233; O-Acetyl-(-)-hyoscine Hydrobromide; 6β,7β-Epoxy-1αH,5αH-tropan-3α-ol (-)-Tropate (Ester) Acetate Hydrobromide; (-)-Scopolamine Acetate Hydrobromide

DATABASE IDS

• CAS Number: 5027-67-8

PROPERTIES

• Apperance: White Solid
• Solubility: Ethanol (hot); Methanol

DETAILS

Description (English)

Scopolamine Hydrobromide (S200000) derivative. An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.

REFERENCES

• Brand, J.J., et al.: Lancet, 2, 232 (1970)
• Bowles, J.B., et al.: Anaesthesia, 34, 476 (1970)
• Clissold, S.P., et al.: Drugs, 29, 189 (1970)
• Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1970)