(-)-α-Acetylmethadol Hydrochloride

• Catalog No.: A186325
• CAS Number: 43033-72-3
• M. F.: C23H32ClNO2
• M. W.: 389.95868

SYNONYMS

• IUPAC name: (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate hydrochloride
• IUPAC Traditional name: levomethadyl acetate hydrochloride
• Synonyms: l-α-Acetylmethadol Hydrochloride; α-(-)-Acetylmethadol Hydrochloride; (-)-6-(Dimethylamino)-4,4-diphenyl-3-heptanol Acetate (Ester) Hydrochloride; (-)-α-Acetylmethadol; levomethadyl acetate hydrochloride; (3S,6S)-(-)- 6-(Dimethylamino)-4,4-diphenyl-3-heptanol Acetate (Ester) Hydrochloride; (αS)-β-[(2S)-2-(Dimethylamino)propyl]-α-ethyl-β-phenylbenzeneethanol Acetate (Ester) Hydrochloride; Hydrochloride LAAM; Levacetylmethadol Hydrochloride; Levo-α-acetylmethadol Hydrochloride; Levomethadyl Hydrochloride

DATABASE IDS

• CAS Number: 43033-72-3

DETAILS

Description (English)

The enantiomer of (+)-α-Acetylmethadol (A186320). A synthetic opioid similar in structure to Methadone (M225865) used in the treatment of opiate dependence. It acts as a μ-opioid receptor agonist. It also acts as a potent, noncompetitive α3β4 neuronal nic

REFERENCES

• Billings, R.E. et al.: Life Sci., 14, 1437 (1974)
• Galici, R. et al.: Pharmacol. Biochem. Behav., 81, 626 (1974)
• Xiao, Y. et al.: J. Pharmacol. Exp. Therap., 299, 366 (1974)