(+)-α-Acetylmethadol Hydrochloride_Molecular_structure_CAS_53757-35-0)

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(+)-α-Acetylmethadol Hydrochloride
Catalog No.	A186320	Name	Toronto Research Chemicals
CAS Number	53757-35-0	Website	http://www.trc-canada.com
M. F.	C23H32ClNO2	Telephone	+1 (416) 665-9696
M. W.	389.95868	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 159352

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SYNONYMS

IUPAC name

(3S,6R)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate hydrochloride

IUPAC Traditional name

betacetylmethadol hydrochloride

Synonyms

(αR)-β-[(2R)-2-(dimethylamino)propyl]-α-ethyl-β-phenylbenzeneethanol 1-Acetate Hydrochloride

α-d-Acetylmethadol hydrochloride

R-(R*,R*)]-β-[2-(dimethylamino)propyl]-α-ethyl-β-phenylbenzeneethanol Acetate (Ester) Hydrochloride

α-Acetylmethadol hydrochloride

DATABASE IDS

CAS Number

53757-35-0

PROPERTIES

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DETAILS

Description (English)

The enantiomer of (-)-α-Acetylmethadol (A186325), a synthetic opioid similar in structure to Methadone (M225865) used in the treatment of opiate dependence. (+)-α-Acetylmethadol is more effective than (-)-α-Acetylmethadol in competing for both 3H-ligands

REFERENCES

Billings, R.E. et al.: Life Sci., 14, 1437 (1974)
Galici, R. et al.: Pharmacol. Biochem. Behav., 81, 626 (1974)
Xiao, Y. et al.: J. Pharmacol. Exp. Therap., 299, 366 (1974)
Horng, J.S. et al.: Res. Comm. Chem. Pathol. Pharmacol., 14, 621 (1974)