21-Acetyloxy Budesonide-d8

• Catalog No.: A164487
• M. F.: C27H36O7
• M. W.: 472.57054

SYNONYMS

• IUPAC name: 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-9,13-dimethyl-16-oxo-6-(^2H₇)propyl(6-^2H)-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-14,17-dien-8-yl]-2-oxoethyl acetate
• IUPAC Traditional name: 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-9,13-dimethyl-16-oxo-6-(^2H₇)propyl(6-^2H)-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-14,17-dien-8-yl]-2-oxoethyl acetate
• Synonyms: 21-(Acetoxy)-16α,17α-(butylidenedioxy)-11β-hydroxypregna-1,4diene-3,20-dione-d8; (11β,16α)-21-(Acetyloxy)-16,17-[butylidenebis(oxy)]-11-hydroxy-pregna-1,4-diene-3,20-dione

PROPERTIES

• Apperance: White Solid
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate

DETAILS

Description (English)

Protected Budesonide-d8 (B689492), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.

REFERENCES

• Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979)
• Roth, G., et al.: J. Pharm. Sci., 69, 766 (1979)
• Clissold, S.P., et al.: Drugs, 28, 485 (1984)