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2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconohydroximo-1,5-lactone_Molecular_structure_CAS_132063-03-7)
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2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconohydroximo-1,5-lactone

Catalog No. A142425 Name Toronto Research Chemicals
CAS Number 132063-03-7 Website http://www.trc-canada.com
M. F. C15H18N2O6 Telephone +1 (416) 665-9696
M. W. 322.31322 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 158864

SYNONYMS

IUPAC name
N-[(4aR,7R,8R,8aS)-8-hydroxy-6-(hydroxyimino)-2-phenyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-7-yl]acetamide
IUPAC Traditional name
N-[(4aR,7R,8R,8aS)-8-hydroxy-6-(hydroxyimino)-2-phenyl-hexahydropyrano[3,2-d][1,3]dioxin-7-yl]acetamide
Synonyms
2-(Acetylamino)-2-deoxy-N-hydroxy-4,6-O-[(R)-phenylmethylene]-D-gluconimidic Acid δ-Lactone

DATABASE IDS

CAS Number 132063-03-7

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 229-231°C
Solubility DMSO
Solubility Methanol
MSDS Link Download

DETAILS

Description (English)
2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconohydroximo-1,5-lactone is used in synthesis of 2-acetamido-2-deoxy-D-gluconohydroximolactone (PUGNAc), a strong inhibitor of β-N-acetylglucosaminidases.

REFERENCES

  • Horsch, M., et al.: Eur. J. Biochem., 197, 815 (1991)
  • Horsch, M., et al.: Eur. J. Biochem., 237, 476 91996), Fernandes, M., et al.: J. Biol. Chem., 272, 814 (1991)