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(R)-Acenocoumarol

Catalog No. A130790 Name Toronto Research Chemicals
CAS Number 66556-77-2 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
4-hydroxy-3-[(1R)-1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one
IUPAC Traditional name
(R)-acenocoumarol
Synonyms
(R)-(+)-Acenocoumarol
(+)-Acenocoumarin
(R)-(+)-Nicoumalone
(R)-4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one
(+)-3-(α-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin

DATABASE IDS

CAS Number 66556-77-2

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
R-Enantiomer of Acenocoumarol. Vitamin K antagonist; structurally similar to Warfarin. Anticoagulant.

REFERENCES

  • Cogswell, L., et al.: J. Pharm. Sci., 90, 1407 (2001)
  • Nakagawa, T., et al.: Br. J. Clin. Pharmacol., 56, 664 (2001)
  • Fitos, I., et al.: Biochem. Pharmacol., 67, 679 (2001)
  • Nishi, K., et al.: Drug Metab. Dispos., 32, 1069 (2001)