Abiraterone Acetate

• Catalog No.: A108500
• CAS Number: 154229-18-2
• M. F.: C26H33NO2
• M. W.: 391.54572
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2R,5R,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-7,13-dien-5-yl acetate
• IUPAC Traditional name: (1S,2R,5R,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-7,13-dien-5-yl acetate
• Synonyms: (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester); CB 7630

DATABASE IDS

• CAS Number: 154229-18-2

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 127-130°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Abiraterone acetate is a novel steroidal inhibitor of human Cytochrome P450 (17α-Hydroxylase-C17,20-lyase): potential agent for the treatment of prostatic cancer.

REFERENCES

• Denis, L., et al.: Cancer, 72, 3888 (1993)
• Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1993)
• Denmeade, S., et al.: Nat. Rev., 2, 389(1993)
• Scher, H., et al.: J. Clin. Oncol., 23, 8253 (1993)