A2-PE

• Catalog No.: A101000
• CAS Number: 863180-05-6
• M. F.: C77H124NO8P
• M. W.: 1222.784121

SYNONYMS

• IUPAC name: 1-(2-{[2,3-bis(hexadecanoyloxy)propyl phosphonato]oxy}ethyl)-2-[(1E,3E,5E,7E)-2,6-dimethyl-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-1,3,5,7-tetraen-1-yl]-4-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hexa-1,3,5-trien-1-yl]pyridin-1-ium
• IUPAC Traditional name: 1-(2-{[2,3-bis(hexadecanoyloxy)propyl phosphonato]oxy}ethyl)-2-[(1E,3E,5E,7E)-2,6-dimethyl-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-1,3,5,7-tetraen-1-yl]-4-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hexa-1,3,5-trien-1-yl]pyridin-1-ium
• Synonyms: 2-[(1E,3E,5E,7E)-2,6-Dimethyl-8-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3,5,7-octatetraen-1-yl]-1-[4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-4-[(1E,3E,5E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3,5-hexatrien-1-yl]pyridinium; DP-A2-PE

DATABASE IDS

• CAS Number: 863180-05-6

DETAILS

Description (English)

A2-PE is a pigment that forms as a byproduct of the visual cycle in vertebrates, which accumulates in retinal pigment epithelial cells over time leading to decline in cellular function.

REFERENCES

• Liu, J., et al.: J. Biol Chem., 38, 29354 (2000)
• McMahon, A., et al.: Mol. Vision, 13, 258 (2000)
• Kim, S., et al.: Exper. Eye Res., 82, 828 (2000)