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Histamine dihydrochloride

Catalog No. 13-1130 Name Sigma Aldrich
CAS Number 56-92-8 Website http://www.sigmaaldrich.com
M. F. C5H11Cl2N3 Telephone 1-800-521-8956
M. W. 184.06694 Fax
Purity ≥98.0% Email
Storage Chembase ID: 68065

SYNONYMS

Title
组胺 二盐酸盐
IUPAC name
2-(1H-imidazol-4-yl)ethan-1-amine dihydrochloride
IUPAC Traditional name
histamine dihydrochloride
Synonyms
2-(4-Imidazolyl)ethylamine dihydrochloride
2-(4-咪唑)乙胺 二盐酸盐

DATABASE IDS

CAS Number 56-92-8
EC Number 200-298-4
MDL Number MFCD00012703
Beilstein Number 3624116

PROPERTIES

Empirical Formula (Hill Notation) C5H9N3 · 2HCl
Grade SAJ special grade
Purity ≥98.0%
Melting Point 249-252 °C(lit.)
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H315-H317-H319-H334-H335
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P280-P305 + P351 + P338-P342 + P311
Risk Statements 36/37/38-42/43
RTECS MS1575000
Safety Statements 22-26-36/37/39-45
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Description (简体中文)
Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂;H1 的活化可稳定 Ca2+;H2 的活化可刺激神经元腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

REFERENCES