Histamine dihydrochloride

• Catalog No.: 13-1130
• CAS Number: 56-92-8
• M. F.: C5H11Cl2N3
• M. W.: 184.06694
• Purity: ≥98.0%

SYNONYMS

• Title: 组胺 二盐酸盐
• IUPAC name: 2-(1H-imidazol-4-yl)ethan-1-amine dihydrochloride
• IUPAC Traditional name: histamine dihydrochloride
• Synonyms: 2-(4-Imidazolyl)ethylamine dihydrochloride; 2-(4-咪唑)乙胺 二盐酸盐

DATABASE IDS

• CAS Number: 56-92-8
• EC Number: 200-298-4
• MDL Number: MFCD00012703
• Beilstein Number: 3624116

PROPERTIES

• Empirical Formula (Hill Notation): C5H9N3 · 2HCl
• Grade: SAJ special grade
• Purity: ≥98.0%
• Melting Point: 249-252 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H317-H319-H334-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P342 + P311
• Risk Statements: 36/37/38-42/43
• RTECS: MS1575000
• Safety Statements: 22-26-36/37/39-45
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Description (简体中文)

Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂；H1 的活化可稳定 Ca2+；H2 的活化可刺激神经元腺苷酸环化酶的活性；活化一氧化氮合成酶；有效的血管舒张剂。