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Aniline

Catalog No. 01-5610 Name Sigma Aldrich
CAS Number 62-53-3 Website http://www.sigmaaldrich.com
M. F. C6H7N Telephone 1-800-521-8956
M. W. 93.12648 Fax
Purity ≥99.0% Email
Storage Chembase ID: 4459

SYNONYMS

Title
苯胺
IUPAC name
aniline
IUPAC Traditional name
aniline

DATABASE IDS

CAS Number 62-53-3
EC Number 200-539-3
MDL Number MFCD00007629
Beilstein Number 605631

PROPERTIES

Grade SAJ first grade
Linear Formula C6H5NH2
Purity ≥99.0%
Auto Ignition Point 1139 °F
Boiling Point 184 °C(lit.)
Density 1.022 g/mL at 25 °C(lit.)
Flash Point 70 °C
Flash Point 158 °F
Melting Point -6 °C(lit.)
Refractive Index n20/D 1.586(lit.)
Vapor Density 3.22 (185 °C, vs air)
Vapor Pressure 0.7 mmHg ( 25 °C)
Explode Limits 11 %
GHS Pictograms GHS05
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Pictograms GHS09
GHS Signal Word Danger
GHS Hazard statements H301-H311-H317-H318-H331-H341-H351-H372-H400
European Hazard Symbols Toxic Toxic (T)
European Hazard Symbols Nature polluting Nature polluting (N)
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
GHS Precautionary statements P261-P273-P280-P301 + P310-P305 + P351 + P338-P311
RID/ADR UN 1547 6.1/PG 2
Risk Statements 23/24/25-40-41-43-48/23/24/25-50-68
RTECS BW6650000
Safety Statements 26-27-36/37/39-45-46-61-63
Hazard Class 6.1
UN Number 1547
Packing Group 2
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.
Description (简体中文)
Biochem/physiol Actions
The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

REFERENCES