Chloramphenicol

• Catalog No.: 46110
• CAS Number: 56-75-7
• M. F.: C11H12Cl2N2O5
• M. W.: 323.12938

SYNONYMS

• Title: 氯霉素
• IUPAC name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• IUPAC Traditional name: chloromycetin
• Synonyms: D(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide; D-(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; Chloromycetin

DATABASE IDS

• MDL Number: MFCD00078159
• PubChem SID: 24869808
• Beilstein Number: 2225532
• CAS Number: 56-75-7
• EC Number: 200-287-4

PROPERTIES

• Grade: VETRANAL™, analytical standard
• Linear Formula: Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
• Gene Information: human ... CYP1A2(1544)
• Melting Point: 148-150 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H350
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 45
• RTECS: AB6825000
• Safety Statements: 53-45
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
General description
Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706024
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC

Description (简体中文)

Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
General description
Supelco MIP SPE 滤筒标准品。更多信息，请参阅 Supelco 文献 T407075 和 T706024。
法律信息
VETRANAL 商标 Sigma-Aldrich Co. LLC