L-Cysteine

• Catalog No.: DB00151
• CAS Number: 52-90-4
• M. F.: C3H7NO2S
• M. W.: 121.15818

SYNONYMS

• IUPAC name: (2R)-2-amino-3-sulfanylpropanoic acid
• IUPAC Traditional name: L-cysteine
• Synonyms: Cys; Half-cystine; 2-Amino-3-mercaptopropionic acid; 3-mercapto-L-Alanine; L-2-Amino-3-mercaptopropionic acid; L-Cys; L-(+)-Cysteine; Thioserine; Cystein; carbocysteine; b-Mercaptoalanine; (R)-Cysteine; (R)-2-Amino-3-mercaptopropanoic acid

DATABASE IDS

• PubChem SID: 46506553
• PubChem CID: 5862
• CAS Number: 52-90-4

PROPERTIES

• Hydrophobicity(logP): -2.6
• Solubility: 277 mg/mL at 25 oC [BEILSTEIN]

DETAILS

Description (English)

• Drug Groups: approved; nutraceutical
• Description: A thiol-containing non-essential amino acid that is oxidized to form cystine. [PubChem]
• Indication: For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen
• Pharmacology: Due to this ability to undergo redox reactions, cysteine has antioxidant properties. Cysteine is an important source of sulfur in human metabolism, and although it is classified as a non-essential amino acid, cysteine may be essential for infants, the elderly, and individuals with certain metabolic disease or who suffer from malabsorption syndromes. Cysteine may at some point be recognized as an essential or conditionally essential amino acid.
• Affected Organisms: Humans and other mammals
• References: Bulaj G, Kortemme T, Goldenberg DP: Ionization-reactivity relationships for cysteine thiols in polypeptides. Biochemistry. 1998 Jun 23;37(25):8965-72. [Pubmed] ; Baker DH, Czarnecki-Maulden GL: Pharmacologic role of cysteine in ameliorating or exacerbating mineral toxicities. J Nutr. 1987 Jun;117(6):1003-10. [Pubmed]
• External Links: Wikipedia

REFERENCES

• Bulaj G, Kortemme T, Goldenberg DP: Ionization-reactivity relationships for cysteine thiols in polypeptides. Biochemistry. 1998 Jun 23;37(25):8965-72. Pubmed
• Baker DH, Czarnecki-Maulden GL: Pharmacologic role of cysteine in ameliorating or exacerbating mineral toxicities. J Nutr. 1987 Jun;117(6):1003-10. Pubmed