4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

• Catalog No.: A8456
• CAS Number: 30827-99-7
• M. F.: C8H11ClFNO2S
• M. W.: 239.6948432
• Purity: ≥97%

SYNONYMS

• Title: 4-(2-氨乙基)苯磺酰氟 盐酸盐
• IUPAC name: 4-(2-aminoethyl)benzene-1-sulfonyl fluoride hydrochloride
• IUPAC Traditional name: aebsf hydrochloride
• Synonyms: AEBSF

DATABASE IDS

• MDL Number: MFCD00132962
• PubChem SID: 24278240
• CAS Number: 30827-99-7
• Beilstein Number: 7604627

PROPERTIES

• Empirical Formula (Hill Notation): C8H10FNO2S · HCl
• Purity: ≥97%
• Quality Level: PREMIUM
• Solubility: H2O: soluble50 mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.)
• GHS Signal Word: Danger
• GHS Hazard statements: H314
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 3261 8/PG 2
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• Storage Temperature: -20°C
• Hazard Class: 8
• UN Number: 3261
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Recommended concentrations for use are 0.1-1 mM.
Biochem/physiol Actions
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM.

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
建议使用浓度为 0.1 至 1mM。
Biochem/physiol Actions
不可逆的丝氨酸蛋白酶抑制剂。抑制常数与 PMSF 和 DFP 的抑制常数相似。AEBSF 可以抑制胰蛋白酶、糜蛋白酶、纤溶酶、激肽释放酶和凝血酶。作为 PMSF 和 DFP 的替代物，AEBSF 的毒性更低、水溶性和水溶液稳定性更好。AEBSF 已用于细胞培养，使用浓度可达 0.25mM。