O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

• Catalog No.: 12806
• CAS Number: 125700-67-6
• M. F.: C11H16BF4N5O
• M. W.: 321.0822528
• Purity: ≥97.0% (N)

SYNONYMS

• Title: O-苯并三氮唑-N,N,N′,N′-四甲基脲四氟硼酸酯
• IUPAC name: [(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium; tetrafluoroboranuide
• IUPAC Traditional name: [(1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium tetrafluoroborate
• Synonyms: N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate; TBTU; 苯并三唑四甲基四氟硼酸

DATABASE IDS

• MDL Number: MFCD00077413
• CAS Number: 125700-67-6
• Beilstein Number: 7066325
• PubChem SID: 24847819

PROPERTIES

• Linear Formula: C11H16N5O · BF4
• Purity: ≥97.0% (N)
• Melting Point: 205 °C (dec.)(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H228-H315-H319-H335
• European Hazard Symbols: Explosive (E)
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P210-P261-P305 + P351 + P338
• Risk Statements: 2-36/37/38
• Safety Statements: 26-35
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Coupling reagent which is ideally suited for solid-phase peptide synthesis.
Other Notes
Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound1; Coupling reagent which is ideally suited for solid-phase peptide synthesis.2
Packaging
1 kg in glass bottle
5, 25, 100, 250 g in glass bottle

Description (简体中文)

Application
非常适用于固相肽合成的偶联剂。
Other Notes
最近的研究表明，该偶联剂的晶体及溶液结构是胍的 N-氧化物形式，而不是脲化合物1；非常适用于固相肽合成的偶联剂。2
包装
1 kg in glass bottle
5, 25, 100, 250 g in glass bottle