O-(Benzotriazol-1-yl)-N,N,N′,N′-bis(tetramethylene)uronium hexafluorophosphate

• Catalog No.: 12809
• CAS Number: 105379-24-6
• M. F.: C15H20F6N5OP
• M. W.: 431.3163802
• Purity: ≥98.0%

SYNONYMS

• Title: O-(苯并三唑-1-基)-N,N,N′,N′-二(四亚甲基)六氟磷酸脲
• IUPAC name: 1-[(1H-1,2,3-benzotriazol-1-yloxy)(pyrrolidin-1-yl)methylidene]-1λ^5-pyrrolidin-1-ylium; hexafluoro-λ^5-phosphanuide
• IUPAC Traditional name: 1-[(1,2,3-benzotriazol-1-yloxy)(pyrrolidin-1-yl)methylidene]-1λ^5-pyrrolidin-1-ylium hexafluorophosphate
• Synonyms: (苯并三氮唑-1-基氧基)二吡咯烷碳六氟磷酸盐; (Benzotriazol-1-yloxy)dipyrrolidinocarbenium hexafluorophosphate; HBPyU

DATABASE IDS

• PubChem SID: 24847825
• MDL Number: MFCD00191770
• CAS Number: 105379-24-6

PROPERTIES

• Empirical Formula (Hill Notation): C15H20F6N5OP
• Purity: ≥98.0%
• Melting Point: 176 °C (dec.)(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Recent studies show that crystal and solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound3; Non-hygroscopic, extremely reactive reagent for peptide coupling giving low racemization. Reaction by-products are non-cytotoxic4
Packaging
5 g in glass bottle
Application
Catalyst for synthesis of dyes1Reagent for peptide coupling 2

Description (简体中文)

Other Notes
最近的研究显示该偶联试剂的晶体和溶液结构为胍的 N-氧化物形式，而不是脲化合物3；低外消旋作用肽偶联反应的不吸湿强烈反应剂。反应副产物无细胞毒性4
包装
5 g in glass bottle
Application
Catalyst for synthesis of dyes1Reagent for peptide coupling 2