Calcium ionophore III

• Catalog No.: 21186
• CAS Number: 52665-69-7
• M. F.: C29H37N3O6
• M. W.: 523.62058

SYNONYMS

• Title: 钙离子载体 III
• IUPAC name: 5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
• IUPAC Traditional name: 5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
• Synonyms: Calimycin; Calcium Ionophore A23187; 抗生素 A 23187; 钙离子载体; Antibiotic A 23187; 钙离子载体 A23187

DATABASE IDS

• MDL Number: MFCD00151202
• EC Number: 258-084-1
• CAS Number: 52665-69-7
• PubChem SID: 24852712
• Beilstein Number: 1096801

PROPERTIES

• Empirical Formula (Hill Notation): C29H37N3O6
• Grade: Selectophore™
• Quality: function tested
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: DM4676000
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.
General description
Visit our Sensor Applications portal to learn more.
Other Notes
Preparation of an optical chemical sensor for Ca2+ and Mg2+,1
Legal Information
Selectophore is a trademark of Sigma-Aldrich GmbH

Description (简体中文)

Application
高选择性钙离子载体增强对 NMDA 非使君子氨酸的响应。在细胞培养中，通过钙调素依赖结构型一氧化氮合酶刺激一氧化氮的生成。
General description
请访问我们的 传感器应用页面 以了解更多信息。
Other Notes
用于 Ca2+ 和 Mg2+ 光化学传感器的制作1
法律信息
Selectophore 商标 Sigma-Aldrich GmbH