Tunicamycin from Streptomyces sp.

• Catalog No.: 93755
• CAS Number: 11089-65-9
• M. F.: C37H60N4O16
• M. W.: 816.8895

SYNONYMS

• Title: Tunicamycin from Streptomyces sp. 来源于链霉菌 属
• IUPAC name: N-[(2S,3R,4R,5R,6R)-6-[(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl]-2-{[(2S,3S,4S,5R,6S)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxyoxan-3-yl]-12-methyltridec-2-enamide
• IUPAC Traditional name: N-[(2S,3R,4R,5R,6R)-6-[(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl]-2-{[(2S,3S,4S,5R,6S)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxyoxan-3-yl]-12-methyltridec-2-enamide

DATABASE IDS

• CAS Number: 11089-65-9
• Beilstein Number: 6888090
• MDL Number: MFCD00065709

PROPERTIES

• GHS Signal Word: Danger
• GHS Hazard statements: H300
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P264-P301 + P310
• RID/ADR: UN 3462 6.1/PG 2
• Risk Statements: 28
• RTECS: YO7980200
• Safety Statements: 28-37/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 3462
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

General description
mixture of homologous tunicamycins, which differ in the aliphatic side chain
Other Notes
Glucosamine containing antibiotic with cell-surface altering properties, enhances the antiviral and antigrowth effects of interferon1; Many important biochemical functions are inhibited by tunicamycin, such as glycoprotein biosynthesis in yeast2; The synthesis of polyisoprenol sugars in bacteria3

Description (简体中文)

General description
mixture of homologous tunicamycins, which differ in the aliphatic side chain
Other Notes
Glucosamine containing antibiotic with cell-surface altering properties, enhances the antiviral and antigrowth effects of interferon1; Many important biochemical functions are inhibited by tunicamycin, such as glycoprotein biosynthesis in yeast2; The synthesis of polyisoprenol sugars in bacteria3