Home > Compound List > Product Information
Methotrexate hydrate_Molecular_structure_CAS_133073-73-1)
Click picture or here to close

Methotrexate hydrate

Catalog No. 06564 Name Sigma Aldrich
CAS Number 133073-73-1 Website http://www.sigmaaldrich.com
M. F. C20H24N8O6 Telephone 1-800-521-8956
M. W. 472.45456 Fax
Purity 85% Email
Storage Chembase ID: 130867

SYNONYMS

Title
甲氨蝶呤 水合物
IUPAC name
(2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid hydrate
IUPAC Traditional name
hydrate methotrexate
Synonyms
氨甲叶酸 水合物
MTX 水合物
MTX hydrate
4-Amino-10-methylfolic acid hydrate
L-4-Amino-N10-methylpteroylglutamic acid hydrate
L-Amethopterin hydrate
Antifolan hydrate
Methylaminopterin hydrate
对-[(2,4-二氨基喋啶-6)-N-甲基甲氨基]苯甲酰谷氨酸 水合物
L-氨甲喋呤 水合物
氟安定 水合物
氨甲喋呤 水合物

DATABASE IDS

MDL Number MFCD00150847
CAS Number 133073-73-1
EC Number 200-413-8

PROPERTIES

Empirical Formula (Hill Notation) C20H22N8O5 · xH2O
Purity 85%
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H301-H315-H319-H340-H360
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P301 + P310-P305 + P351 + P338-P308 + P313
RID/ADR UN 1544 6.1/PG 3
Risk Statements 46-61-25-36/38
RTECS MA1225000
Safety Statements 53-26-36-45
Hazard Class 6.1
UN Number 1544
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Application
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.4
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Description (简体中文)
Application
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.4
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.

REFERENCES