Luteinizing hormone releasing hormone human acetate salt_Molecular_structure_CAS_71447-49-9)

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Luteinizing hormone releasing hormone human acetate salt
Catalog No.	62690	Name	Sigma Aldrich
CAS Number	71447-49-9	Website	http://www.sigmaaldrich.com
M. F.	C59H83N17O17	Telephone	1-800-521-8956
M. W.	1302.39402	Fax
Purity	≥80% peptide basis	Email
Storage		Chembase ID: 155154

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SYNONYMS

IUPAC name

(2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-{2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamide; bis(acetic acid)

IUPAC Traditional name

(2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-(carbamoylmethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-{2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamide; bis(acetic acid)

Synonyms

Gonadoliberin

Gonadotropin releasing hormone

LH-RH

DATABASE IDS

EC Number	232-895-0
CAS Number	71447-49-9
MDL Number	MFCD00133489

PROPERTIES

Empirical Formula (Hill Notation)	C55H75N17O13
Impurities	≤10% water
Impurities	≤12% acetate
Mol. Weight	Mr 1182.33
Purity	≥80% peptide basis
Purity	≥98.0% (HPLC)
Gene Information	human ... GNRH1(2796)
Solubility	H2O: soluble25 mg/mL, clear, faintly yellow
MSDS Link	Download
Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature	-20°C
German water hazard class	2

DETAILS

Description (English)

Amino Acid Sequence
Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Components
pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Other Notes
free peptide
The principal regulator of the Ca2+-dependent release of gonadotropins, LH and follicle-stimulating hormone1
Biochem/physiol Actions
Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.

Description (简体中文)