5-Bromo-2′-deoxyuridine

• Catalog No.: 16880
• CAS Number: 59-14-3
• M. F.: C9H11BrN2O5
• M. W.: 307.09804
• Purity: ≥99.0% (HPLC)

SYNONYMS

• Title: 5-溴-2′-脱氧尿苷
• IUPAC name: 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 5-bromo-2'-deoxyuridine
• Synonyms: 5-BrdU; 5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶; BUdR; 5-溴脱氧尿苷; 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil; 5-Bromouracil deoxyriboside

DATABASE IDS

• PubChem SID: 24850256
• MDL Number: MFCD00006529
• Beilstein Number: 30395
• CAS Number: 59-14-3
• EC Number: 200-415-9

PROPERTIES

• Empirical Formula (Hill Notation): C9H11BrN2O5
• Purity: ≥99.0% (HPLC)
• Melting Point: 191-194 °C (dec.)(lit.)
• Optical Rotation: [α]20/D +23±1°, c = 1% in H2O
• GHS Signal Word: Danger
• GHS Hazard statements: H340-H361
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• GHS Precautionary statements: P201-P281-P308 + P313
• Risk Statements: 46-61
• RTECS: YU7350000
• Safety Statements: 53-45
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.
Other Notes
Thymidine analogue. Inhibitor of cell differentiation : Review1; Incorporation into DNA for flow cytometric analysis2

Description (简体中文)

Biochem/physiol Actions
用作遗传研究中诱变剂的胸苷类似物。在 S 期可选择性结合到细胞 DNA 中。
Other Notes
Thymidine analogue. Inhibitor of cell differentiation : Review1; Incorporation into DNA for flow cytometric analysis2