3′-Azido-3′-deoxythymidine

• Catalog No.: 11546
• CAS Number: 30516-87-1
• M. F.: C10H13N5O4
• M. W.: 267.24132
• Purity: ≥99.0% (HPLC)

SYNONYMS

• Title: 3′-叠氮-3′-脱氧胸苷
• IUPAC name: 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: zidovudine
• Synonyms: ZDV; Zidovudine; 齐多夫定; azidothymidine; AZT; 叠氮胸苷

DATABASE IDS

• Beilstein Number: 3595791
• MDL Number: MFCD00006536
• CAS Number: 30516-87-1

PROPERTIES

• Empirical Formula (Hill Notation): C10H13N5O4
• Impurities: ≤0.5% water
• Purity: ≥99.0% (HPLC)
• Melting Point: 113-115 °C(lit.)
• Solubility: H2O: soluble50 mg/mL, clear, colorless to slightly yellow
• GHS Signal Word: Warning
• GHS Hazard statements: H351
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P281
• Risk Statements: 40
• RTECS: XP2072000
• Safety Statements: 36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Reverse transcriptase inhibitor active against HIV-1 virus.
Other Notes
A potent, selective inhibitor of human immunodeficiency virus replication in MT-4 and ATH8 cells1

Description (简体中文)

Biochem/physiol Actions
对 HIV-1 病毒有效的逆转录酶抑制剂。
Other Notes
A potent, selective inhibitor of human immunodeficiency virus replication in MT-4 and ATH8 cells1