(R)-5-(Hydroxymethyl)-2-pyrrolidinone

• Catalog No.: 55820
• CAS Number: 66673-40-3
• M. F.: C5H9NO2
• M. W.: 115.13046
• Purity: ≥99.0% (sum of enantiomers, HPLC)

SYNONYMS

• Title: (R)-(-)-5-(羟甲基)-2-吡咯烷酮
• IUPAC name: (5R)-5-(hydroxymethyl)pyrrolidin-2-one
• IUPAC Traditional name: (5R)-5-(hydroxymethyl)pyrrolidin-2-one
• Synonyms: D-Pyroglutaminol; D-焦谷氨醇

DATABASE IDS

• CAS Number: 66673-40-3
• MDL Number: MFCD00077791
• PubChem SID: 24879728
• Beilstein Number: 3587974

PROPERTIES

• Empirical Formula (Hill Notation): C5H9NO2
• Grade: puriss.
• Purity: ≥99.0% (sum of enantiomers, HPLC)
• Melting Point: 79-85 °C
• Optical Rotation: [α]/D -30.5±2.0°, c = 5 in ethanol
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Versatile chiral building block and auxiliary, used e.g. for the synthesis of azaprostaglandins or 4,5-diaminovalerate1,2,3; The bicyclic N,O-benzylidene acetal allows enantioselective derivatization of the pyrrolidinone nucleus4,5

Description (简体中文)

Other Notes
多功能手性结构单元和辅助剂，用于如合成氮杂前列腺素或 4,5-二氨基戊酸酯1,2,3；双环 N,O-亚苄基缩醛允许吡咯烷酮核的立体选择性衍生化反应4,5