Rotenone

• Catalog No.: 45656
• CAS Number: 83-79-4
• M. F.: C23H22O6
• M. W.: 394.41718

SYNONYMS

• Title: 鱼滕精
• IUPAC name: (1S,6R,13S)-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0^3,^1^1.0^4,^8.0^1^4,^1^9]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
• IUPAC Traditional name: cube root

DATABASE IDS

• Beilstein Number: 6773081
• EC Number: 201-501-9
• MDL Number: MFCD09025614
• CAS Number: 83-79-4
• PubChem SID: 24869200

PROPERTIES

• Empirical Formula (Hill Notation): C23H22O6
• Grade: PESTANAL®, analytical standard
• Boiling Point: 210-220 °C/0.5 mmHg(lit.)
• Melting Point: 159-164 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335-H410
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P273-P301 + P310-P305 + P351 + P338-P501
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25-36/37/38-50/53
• RTECS: DJ2800000
• Safety Statements: 22-24/25-36-45-60-61
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.
Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
Legal Information
PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH

Description (简体中文)

Biochem/physiol Actions
Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.
Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
法律信息
PESTANAL 注册商标 Sigma-Aldrich Laborchemikalien GmbH