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Quinine hemisulfate salt monohydrate_Molecular_structure_CAS_207671-44-1)
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Quinine hemisulfate salt monohydrate

Catalog No. 22642 Name Sigma Aldrich
CAS Number 207671-44-1 Website http://www.sigmaaldrich.com
M. F. C40H54N4O10S Telephone 1-800-521-8956
M. W. 782.94256 Fax
Purity Email
Storage Chembase ID: 130841

SYNONYMS

Title
奎宁 半硫酸盐 一水合物
IUPAC name
bis((R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol) sulfuric acid dihydrate
IUPAC Traditional name
bis(quinine) sulfuric acid dihydrate
Synonyms
硫酸奎宁
Chinini sulfas
Quinine sulfate (2:1) (salt) dihydrate

DATABASE IDS

Beilstein Number 6113937
CAS Number 207671-44-1
MDL Number MFCD00150790
PubChem SID 24853567

PROPERTIES

Empirical Formula (Hill Notation) C20H24N2O2 · 0.5H2O4S · H2O
Grade Ph Eur
Pharmacopeia testing & handling conforms to Pharmacopeia
Melting Point ~225 °C (dec.)(lit.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26
German water hazard class 3

DETAILS

Description (English)
Application
Used to study the toxicity of heme (FP)-complexes.
Biochem/physiol Actions
Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Description (简体中文)
Application
Used to study the toxicity of heme (FP)-complexes.
Biochem/physiol Actions
钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂;最初从南美树木的金鸡纳科中分离出来的生物碱。

REFERENCES