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Eserine

Catalog No. 45710 Name Sigma Aldrich
CAS Number 57-47-6 Website http://www.sigmaaldrich.com
M. F. C15H21N3O2 Telephone 1-800-521-8956
M. W. 275.34614 Fax
Purity ≥98.0% (N) Email
Storage Chembase ID: 856

SYNONYMS

Title
毒扁豆碱
IUPAC name
(3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate
IUPAC Traditional name
physostigmine
Synonyms
伊色林
Physostigmine

DATABASE IDS

EC Number 200-332-8
PubChem SID 24869283
MDL Number MFCD00151090
CAS Number 57-47-6
Beilstein Number 91230

PROPERTIES

Empirical Formula (Hill Notation) C15H21N3O2
Purity ≥98.0% (N)
Gene Information human ... ACHE(43), APP(351), BCHE(590)mouse ... Ache(11423), Bche(12038), Chrm1(12669)rat ... Ache(83817), Bche(65036), Chrm2(81645)
Flash Point >100 °C
Flash Point >212 °F
Melting Point 102-104 °C(lit.)
Melting Point 102-106 °C
Optical Rotation [α]20/D -77±1°, c = 1.7% in chloroform
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H300-H330
European Hazard Symbols Highly toxic Highly toxic (T+)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P260-P264-P284-P310
RID/ADR UN 1544 6.1/PG 1
Risk Statements 26/28
RTECS TJ2100000
Safety Statements 25-45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 1544
Packing Group 1
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.
Description (简体中文)
Biochem/physiol Actions
乙酰胆碱酯酶抑制剂越过血脑屏障并与乙酰胆碱酯酶形成缓慢降解的氨基甲酰酶络合物。

REFERENCES