Eserine

• Catalog No.: 45710
• CAS Number: 57-47-6
• M. F.: C15H21N3O2
• M. W.: 275.34614
• Purity: ≥98.0% (N)

SYNONYMS

• Title: 毒扁豆碱
• IUPAC name: (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate
• IUPAC Traditional name: physostigmine
• Synonyms: 伊色林; Physostigmine

DATABASE IDS

• EC Number: 200-332-8
• PubChem SID: 24869283
• MDL Number: MFCD00151090
• CAS Number: 57-47-6
• Beilstein Number: 91230

PROPERTIES

• Empirical Formula (Hill Notation): C15H21N3O2
• Purity: ≥98.0% (N)
• Gene Information: human ... ACHE(43), APP(351), BCHE(590)mouse ... Ache(11423), Bche(12038), Chrm1(12669)rat ... Ache(83817), Bche(65036), Chrm2(81645)
• Flash Point: >100 °C
• Flash Point: >212 °F
• Melting Point: 102-104 °C(lit.)
• Melting Point: 102-106 °C
• Optical Rotation: [α]20/D -77±1°, c = 1.7% in chloroform
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H330
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P284-P310
• RID/ADR: UN 1544 6.1/PG 1
• Risk Statements: 26/28
• RTECS: TJ2100000
• Safety Statements: 25-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.

Description (简体中文)

Biochem/physiol Actions
乙酰胆碱酯酶抑制剂越过血脑屏障并与乙酰胆碱酯酶形成缓慢降解的氨基甲酰酶络合物。