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N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine_Molecular_structure_CAS_16858-02-9)
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N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine

Catalog No. 87641 Name Sigma Aldrich
CAS Number 16858-02-9 Website http://www.sigmaaldrich.com
M. F. C26H28N6 Telephone 1-800-521-8956
M. W. 424.54072 Fax
Purity ≥98.0% (NT) Email
Storage Chembase ID: 104575

SYNONYMS

IUPAC name
{2-[bis(pyridin-2-ylmethyl)amino]ethyl}bis(pyridin-2-ylmethyl)amine
IUPAC Traditional name
{2-[bis(pyridin-2-ylmethyl)amino]ethyl}bis(pyridin-2-ylmethyl)amine
Synonyms
TPEN

DATABASE IDS

CAS Number 16858-02-9
PubChem SID 24888924
MDL Number MFCD00036918
Beilstein Number 4211982

PROPERTIES

Empirical Formula (Hill Notation) C26H28N6
Purity ≥98.0% (NT)
Melting Point 110-112 °C
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
TPEN is a membrane-permeable zinc chelator; decreased the intracellular level of zinc and induced apoptosis (i.e., cell shrinkage and formation of apoptotic bodies with DNA fragmentation and formation of a typical DNA ladder pattern).
Other Notes
Chelating agent for intracellular heavy metals1
Description (简体中文)
Biochem/physiol Actions
TPEN is a membrane-permeable zinc chelator; decreased the intracellular level of zinc and induced apoptosis (i.e., cell shrinkage and formation of apoptotic bodies with DNA fragmentation and formation of a typical DNA ladder pattern).
Other Notes
Chelating agent for intracellular heavy metals1

REFERENCES