N,N′-Disuccinimidyl carbonate

• Catalog No.: 43720
• CAS Number: 74124-79-1
• M. F.: C9H8N2O7
• M. W.: 256.16902
• Purity: ≥95.0% (NMR)

SYNONYMS

• Title: N,N′-二琥珀酰亚胺基碳酸酯
• IUPAC name: bis(2,5-dioxopyrrolidin-1-yl) carbonate
• IUPAC Traditional name: bis(2,5-dioxopyrrolidin-1-yl) carbonate
• Synonyms: N-琥珀酰氨基碳酸酯; DSC; N-Succinimidyl carbonate; 二(N-琥珀酰亚胺基)碳酸酯; Di(N-succinimidyl) carbonate

DATABASE IDS

• PubChem SID: 24867355
• MDL Number: MFCD00009767
• CAS Number: 74124-79-1
• EC Number: 277-730-3
• Beilstein Number: 1499137

PROPERTIES

• Empirical Formula (Hill Notation): C9H8N2O7
• Grade: purum
• Impurities: ~3% N-hydroxysuccinimide (NMR)
• Purity: ≥95.0% (NMR)
• Melting Point: 190 °C (dec.)(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P301 + P310-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• Safety Statements: 26-37/39
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Convenient reagent for preparing N-succinimidyl esters of N-protected amino acids and other acids;1 activated carbonate, e.g. synthesis of ureas and carbamates;2,3 coupling of ligands to proteins (via lysines).4

Description (简体中文)

Other Notes
用于制备 N-保护性氨基酸和其他酸的 N-琥珀酰亚胺基酯的简便试剂；1活化碳酸盐，例如合成尿素和氨基甲酸盐；2,3将配体偶联至蛋白质（通过赖氨酸）。4