Choline chloride

• Catalog No.: 26980
• CAS Number: 67-48-1
• M. F.: C5H14ClNO
• M. W.: 139.62376
• Purity: ≥97.0% (AT)

SYNONYMS

• Title: 氯化胆碱
• IUPAC name: (2-hydroxyethyl)trimethylazanium chloride
• IUPAC Traditional name: choline chloride
• Synonyms: (2-Hydroxyethyl)trimethylammonium chloride; (2-羟乙基)三甲基氯化铵

DATABASE IDS

• CAS Number: 67-48-1
• Beilstein Number: 3563126
• MDL Number: MFCD00011721
• EC Number: 200-655-4

PROPERTIES

• Linear Formula: (CH3)3N(Cl)CH2CH2OH
• Purity: ≥97.0% (AT)
• Melting Point: 302-305 °C (dec.)(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: KH2975000
• Safety Statements: 26-36
• German water hazard class: 1

DETAILS

Description (English)

Substrates
Choline acetyltransferase substrate
Biochem/physiol Actions
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1.

Description (简体中文)

Substrates
胆碱乙酰基转移酶底物
Biochem/physiol Actions
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1.