Bromotris(dimethylamino)phosphonium hexafluorophosphate

• Catalog No.: 18570
• CAS Number: 50296-37-2
• M. F.: C6H18BrF6N3P2
• M. W.: 388.0691612
• Purity: ≥98.0% (AT)

SYNONYMS

• Title: 溴代三(二甲基氨基)磷鎓六氟磷酸盐
• IUPAC name: bromotris(dimethylamino)phosphanium; hexafluoro-λ^5-phosphanuide
• IUPAC Traditional name: bromotris(dimethylamino)phosphanium hexafluorophosphate
• Synonyms: BroP; Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate

DATABASE IDS

• MDL Number: MFCD00191864
• PubChem SID: 24851158
• CAS Number: 50296-37-2

PROPERTIES

• Grade: purum
• Linear Formula: BrP[N(CH3)2]3PF6
• Purity: ≥98.0% (AT)
• Melting Point: >300 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H314-H350
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P280-P305 + P351 + P338-P310
• RID/ADR: UN 3263 8/PG 2
• Risk Statements: 45-34
• Safety Statements: 53-26-36/37/39-45
• Hazard Class: 8
• UN Number: 3263
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

General description
may contain ≥0.1% HMPT
Other Notes
Coupling reagent for N-methyl amino acids without racemization7; Coupling of α,α-dialkyl amino acids, e.g. AIB8
Application
Reagent for: Conjugate addition of nitroalkanes to an acrylate equivalent1 A novel polymer supported approach to nucleoside modification2 Asymmetric hydrogenations3 Peptide coupling4 Pyrrolidine hydroxylation5 Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA6

Description (简体中文)

General description
可能含 ≥0.1% 的 HMPT
Other Notes
无外消旋作用的 N-甲基氨基酸偶联试剂7；可用于 α,α-二烷基氨基酸，如 AIB 的偶联反应8
Application
Reagent for: Conjugate addition of nitroalkanes to an acrylate equivalent1 A novel polymer supported approach to nucleoside modification2 Asymmetric hydrogenations3 Peptide coupling4 Pyrrolidine hydroxylation5 Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA6