Home > Compound List > Product Information
Di-tert-butyl dicarbonate_Molecular_structure_CAS_24424-99-5)
Click picture or here to close

Di-tert-butyl dicarbonate

Catalog No. 34660 Name Sigma Aldrich
CAS Number 24424-99-5 Website http://www.sigmaaldrich.com
M. F. C10H18O5 Telephone 1-800-521-8956
M. W. 218.24692 Fax
Purity ≥98.0% (GC) Email
Storage Chembase ID: 85817

SYNONYMS

Title
二碳酸二叔丁酯
IUPAC name
di-tert-butyl dicarbonate
IUPAC Traditional name
di-tert-butyl dicarbonate
Synonyms
二叔丁基二碳酸酯
焦碳酸二叔丁酯
Di-tert-butyl pyrocarbonate
BOC anhydride

DATABASE IDS

MDL Number MFCD00008805
CAS Number 24424-99-5
PubChem SID 24861420
Beilstein Number 1911173
EC Number 246-240-1

PROPERTIES

Linear Formula [(CH3)3COCO]2O
Purity ≥98.0% (GC)
Boiling Point 56-57 °C/0.5 mmHg(lit.)
Density 0.95 g/mL at 25 °C(lit.)
Flash Point 37 °C
Flash Point 98.6 °F
Melting Point 22-26 °C
Melting Point 23 °C(lit.)
Refractive Index n20/D 1.409(lit.)
GHS Pictograms GHS02
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H226-H315-H317-H319-H330-H335
European Hazard Symbols Highly toxic Highly toxic (T+)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
GHS Precautionary statements P260-P280-P284-P305 + P351 + P338-P310
RID/ADR UN 2929 6.1/PG 1
Risk Statements 10-26-36/37/38-43
RTECS HT0230000
Safety Statements 7/9-16-26-28-36/37-45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2929
Packing Group 1
German water hazard class 3

DETAILS

Description (English)
Application
Reagent for the introduction of the Boc protecting group.
Other Notes
Reagent for the clean and rapid introduction of the acid labile BOC-protecting group in amino acids, peptides and proteins; 1 N-BOC-ylation of amides; 2,3 N-BOC-ylation of sensitive compounds under non-aqueous conditions.4
Warning
Hydrolyzes to t-butanol and CO2; causes internal pressure in bottle if exposed to moisture.
Description (简体中文)
Application
用于引入叔丁氧羰基保护基团的试剂。
Other Notes
用于在氨基酸、多肽和蛋白质中清除和快速引入酸不稳定的丁氧羰基保护基团的试剂;1酰胺的 N-BOC 基化;2,3无水条件下敏感化合物的 N-BOC 基化。4
Warning
水解为叔丁醇和 CO2;暴露在潮湿环境中会导致瓶内压力增大。

REFERENCES